By far the most epic loot my toon ever got was his Albino Drake. Before patch 3.02 came out I had done just about everything you could do in wow to date so I rolled my character on the PTR. After checking out all the cool stuff they added I took a good hard look at the achievement and noticed the Albino Drake reward. From then on I was dead set on getting that before WoTLK was released. So I did rep grinding for as many mounts as I possibly could and within about a week of 3.02 going live i had my drake WOOOOOOOT
Back in the day when UBRS was the hot place to be, I used to PUG my way with my mage. When my Magister's Robe finally dropped from Drakk, I almost cried I was so happy.
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Epic for me was returning back to Kara with my alt warlock near the end of BC, and doing a 2 hour run with a pug. After having tanked it and struggled with it at the onset of BC, it was just crazy to see how much gear and experience made it so much more enjoyable.
Getting my frozen orb in my first WOLK heroic is my favorite drop of the xpac b/c it led to my Nesginwary 4000. The orb dropped in heroic Nexus but some nub hit need on accident so we decided to re-roll. I was devistated when I rolled a modest 63 but I still won anyway. Good times.
My most Epic loot that i have gotten was obtained back in Vanilla Wow where our guild was running BWL and i was the new person in the guild and haven't run it yet. I ended up making 4 of the 8 T2 set pieces in that one night considering everyone in the class had the items i got.
On our first crack at Prince in Kara, we had him nearly dead when most of the raid wiped. I was tanking and had only a healer and an undergeared ret pally left to help, but we managed to take down that last couple percent on him.We loot the body, and it's the T4 helm. I rolled in the mid-60s and figured it was a goner, but somehow everyone else rolled lower. Having started playing WoW a few months before BC, it was my first piece of T-anything and I was thrilled not only with the gear, but the way we held on to drop Prince.Cheers!Zeke
My epic drop was not one but 2 world epic drops back to back while farming in Badlands. On my warlock back in vanilla wow grinding my way to 60. I ended up with http://www.wowhead.com/?item=1447 and http://www.wowhead.com/?item=868 needless to say I really couldn't use the items but was able to make a few gold that day. To this day people still say your lucky to ever see a world epic drop and even fewer can say they had 2 drop back to back. That has to be a 1 in a million chance to have drops fall like that.
I haven't gotten any 'epic' drops yet... But my best drop was the http://www.wowhead.com/?item=1718#. I was in a ZF runthrough, and random basilisk dropped em. ^^ Got me 500g.
My most "Epic Lewt" was from Keleseth, in my guild's first Utgarde Keep run. It's not a heroic drop or anything, but Keleseth's Blade of Evocation kicked the snot out of the staff I had. I paired this blade up with my Manual of the Tides for a nice-looking and -performing setup.
I have never gotten an Epic drop yet, but just last night I had what I considered an epic battle! I soloed Sarathstra in Dragonblight as a 75 Siphon Life/Felguard specced Warlock. Took about 10 minutes to kill it, but she finally fell. Was the best battle I ever had, probably because it felt like a huge personal acheivement after it was over.