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I would have to say the Bow of Searing Arrows, it was really awesome, was the first epic across 3 toons, and the firing animation with flaming arrows was cool.
On the third time doing kara, there was only me(ele shaman) and a resto shaman that needed spell power gear. So we did kara, almost every boss we each got a loot in!
LOL My most epic drop was after farming Winterspring for months to get my rep to exhaulted. My guildies thought I was crazy and should have been in OL long b4 I finally went there. I got my Wintersabre mount finally and it was/is the coolest mount ever. I'm still trying to decide if I have enough stubbornness to get it for my other two toons...probably not. Another thing that came from Winterspring was getting exhaulted with the Timbermaw and getting the Timbermaw defender trinket. Both of those are the coolest most epic things I have gotten while playing my Frost Mage.
Gotta say, most epic drop I've ever had was when I managed to get my hand of rag back in the day =)
During the Hallow's End event this year, I became kinda obsessed with getting the Horseman's Helm. I went every day trying to get the helmet with sometimes more than one group of people a day. One day it finally dropped but there happened to be a dps warrior in the group so I let him have it since he needed it more than I did being a tank. I kinda hated myself but I couldnt bring myself to take it from him. Every day I kept trying to get the helmet but it never dropped again until the very last try on the last day of the event. I went nuts.. I was like OMFG OMFG OMFG etc.etc. I was like can I PLEASE have it? And of course, being guildies and knowing how much I'd been wanting it they let me have it. I was so happy that I gave 200g to the people in the party and then deposited 444g in the guild vault. I know its not that great a helmet, especially for a tank but I just love the laugh.. Not to mention it looks pretty funny. I still keep it in my bank and every now and then when I'm bored of playing I go put it on and laugh with it.
I have only played the online game a short amount of time, so it's hard to answer this question in the defined format. However, I play the TCG version of WoW and at the recent Realms Championships I won several packs and pulled an Owned Loot from one of my packs. This was epic for me because it was the first time I have EVER pulled a loot card......and on top of that I had won the pack!
My most epic loot I got just a few hours ago. Since wrath hit I've been grinding argent crusade rep to get the title and (since I'm a holy paladin) the helm and ring. I've been running instances with my tabard on, though I've also had to grind up Wyrmrest Accord and Dalaran for some upgrades as well. I finally got halfway through revered on Argent Crusade so I knuckled down and kept that tabard on the last few days. I've also been grinding the Troll Patrol quests, always getting them done in under 20 minutes. The closest one was 2 minutes left, scared the crap out of me that I wouldn't get the extra bonus, but I still haven't done that daily group in over 18 minutes time. Did a few runs tonight and got within 1500 rep from exalted or so, and I hadn't done my dailys yet. So I did them and I was around 800 away from exalted and was about to go to bed when I noticed that they were going to reset soon. So I went and did some other dailys until it reset.As soon as they did I flew straight to those dailys I had just done and just as I was turning in another Troll Patrol (with 9 minutes left to spare) I got both achievements for the title and getting their reputation to exalted. I quick switched my title and then flew over to Icecrown to get my two new epics.Another short trip to Dalaran to port to Stormwind, three gems purchased at the auction house for my helm and chest piece... and now I'm sitting at 19k mana and have two more epic items. Definitely an epic night!
I'd say it would be the Cursed Vision of Sargeras, but that's only a piece of gear. True epic only a battle can be, like soloing SM as a prot warrior in one huge pull.
Even though i cannot win this contest since i'm not from United States i'll still post my most "epic lewt". It "dropped" when my guild got Realm first kill on Malygos 25 and we all got this Achievement http://www.wowhead.com/?achievement=1400 and "the Magic Seeker" title. The most important loot for me is what my guild achieves PvE wise and that definitely was one epic "drop".
I'm fairly cheap when it comes to buying things on the Auction House, but on my first 70 in BC I really wanted the epic robe set on my priest for the awesome stats for my poorly geared character. It took days and hours worth of farming, but it has to be the most rewarding thing I have done in WoW. Had I bought everything as originally intended, I probably wouldn't have been so proud of myself.
The day I got my worg pup was epic in my case...I soloed it as a hunter at a very low level...it took about 30 times of rezing and learning the place until I got him....worth it though! :)
The most epic loot for me would have to be spellpower mace off Prince in Karazhan. I ran that instance for probably a year and a half without it EVER dropping. (or at least while i was not in the group.) Once we got the new Badge rewards from Shattered Sun content patch, I saved my badges for the badge spellpower mace.Around badge number 145 or so, the mace finally dropped while I was there! >.< I debated for a moment and decided the badge mace would still be the best for me. But since I was the Disenchanter, I had it in my inventory anyway... so I simply donated 2 voids out of my own stash, and kept the mace just to spite Prince >O! lol